Single Use Biporocessing Market 2022 - Market Size & Forecast, Industry Trends, Manufacturers Analysis, & Opportunities 2030

The global single-use bioprocessing market is expected to register growth at a CAGR of 15.5% during the forecast period of 2022-2030.

Single-use bioprocessing is a rapidly emerging technology that involves the development of disposable bioprocessing equipment and accessories to manufacture biopharmaceutical products. These solutions and products are designed to be employed once and then dispensed and are usually created from plastic components that are sealed utilizing gamma irradiation and sterilized. Most often, these products are used for the manufacturing of plant cell cultivations, vaccines, monoclonal antibodies and specific cell therapies. Single use bioprocessing helps in combating global drug shortage problem.

The technology aids in making the process of manufacturing drugs cheaper, faster and simpler. This technology provides ultimate speed, flexibility, notable reduction in capital cost and facility construction time, and enhancement of manufacturing reproducibility by offering durability, strength, and temperature resistance.  As a result, it is regarded as a commercially viable approach to attaining maximum process productivity and efficiency by its end-users worldwide.

GROWTH DRIVERS:

Factors such as the burgeoning demand and adoption of single-use bioprocessing products globally during the developmental stages of drugs and the manufacturing of several biopharmaceuticals due to their commercial advantages;  the proliferating demand for biopharmaceuticals & energy efficiency; the increasing need to reduce water wastage; the growing number of vendors offering robust disposables for commercial manufacturing of biopharmaceuticals and the surging adoption of disposable technologies attributable to the low risk of product cross-contamination of SUB technologies are the primary factors driving the growth of the global single use bioprocessing market.

Additionally, the escalating number of technological advancement s in products such as in disposable probes & sensors, stirring systems, film technologies and bioreactor designs along with the incorporation of automation in the bioprocessing industry is aiding in the enhancement of single-use-based biomanufacturing processes considerably. These technological advancements have resulted in the advent of analytical models (also referred to as intelligent biomanufacturing) based on big data machine-learning for the prediction of errors and improving the accuracy during medical procedures, which thereby fastens the biomanufacturing efficiency significantly. Due to this, the adoption of the single-use bioprocessing is estimated to grow substantially in the upcoming years.

Moreover, biological approvals have been witnessing an upward trend in the global market since the last few years along with patent expiry.  According to the FDA, a total of 17 biologics were approved in 2018. These included 3 pegylated enzymes, 12 monoclonal antibodies (mAb), 1 fusion protein and 1 protein. This increasing trend of approvals is anticipated to give rise to the biopharmaceuticals manufacturing processs, leading to the enhanced application of single-use bioprocessing over the forecast period.

Furthermore, other factors such as the increasing shifting of several manufactures towards automation and the growing number of initiatives undertaken by them to convert their bioprocessing unit into a single-use unit, the surging preference for single-use products made using high-grade polymer materials and plastic composites due to their integral strength and assistance in reducing operational costs and continuity in biomanufacturing, the rising adoption of disposables among CMOs , the growing number of robust developments in the healthcare sector and the soaring adoption of single-use bioprocessing in pre-clinical and commercial stages are expected to further create ample growth opportunities for the growth of the global single use bioprocessing market during the forecast period.

However, factors such as the high disposable cost and extractability and leachability issues regarding disposable components like plastic bags, the environmental & economic concerns, and stringent regulations pertaining to use of disposable systems in the biopharmaceutical industry are expected to hinder the growth of the global single use bioprocessing market up to some extent during the forecast period.

SINGLE USE BIPOROCESSING MARKET SEGMENTATION:

By Product:

·         Simple & Peripheral Elements

o    Bags

o    Tubing, Filters, Connectors, & Transfer Systems

o    Sampling Systems

o    Probes & Sensors

§  pH Sensor

§  Oxygen Sensors

§  Pressure Sensors

§  Temperature Sensors

§  Conductivity Sensors

§  Flow Sensors

§  Other sensors

o    Others

 

·         Apparatus & Plants

o    Bioreactors, By Capacity

§  Up to 1000L

§  Above 1000L to 2000L

§  Above 2000L

o    Filtration system

o    Mixing, Storage, & Filling Systems 

o    Chromatography Systems

o    Pumps

o    Others

 

·         Work Equipment

o    Cell Culture System

o    Syringes

o    Others

 

By Method:

·         Filtration

·         Storage

·         Cell culture

·         Mixing

·         Purification

 

By Application

·         Monoclonal Antibody Production

·         Vaccine Production

·         Plant Cell Cultivation

·         Patient Specific Cell Therapies

·         Other Applications

 

By Workflow:

·         Upstream

·         Fermentation

·         Downstream

 

By End User:

·         Biopharmaceutical Companies

·         Contract Research Organizations And Contract Manufacturing Organizations (CROS & CMOS)

·         Life Science R&D Companies and Academic & Research Institutes

 

By Region:

·         North America

·         Europe

·         Asia Pacific

·         Latin America

·         Middle East and Africa

 

Based on product, the simple and peripheral elements segment led the global single use bioprocessing market by holding a market share of 48.0% in 2021. The segment is expected to further retain its dominance in the market over the forecast period. The growth of the segment can be attributed to the robust adoption and availability of tubing, transfer systems, filters, and connectors and the proliferating demand for disposable probes and sensors within the biopharmaceutical industry. On the other hand, the apparatus and plants segment is projected to witness growth at the fastest growth rate in the marker during the forecast period.

Based on method, the filtration segment held the largest market share in the global single use bioprocessing market 2021 followed by the storage segment. The segment is anticipated to maintain this trend over the forecast period.

Based on workflow, the upstream segment held 58.0% market share and accounted for the largest share in the global single use bioprocessing market in 2021. The trend is expected to remain unchanged during the forecast period owing to the easy availability of single-use systems for upstream processes including, cell-culture seeding media preparation, aseptic sampling, and others.

Based on end-user, the biopharmaceutical companies segment accounted for a market share of 60.0% and dominated the global single-use bioprocessing market in 2021. The segment is predicted to further continue to stay at the top during the forecast period. The segment’s growth can be majorly attributed to the soaring popularity of disposables amongst contract manufacturers and the growing investments by biomanufacturers in the expansion of their manufacturing capabilities to meet the ever-changing consumer demands.

REGIONAL OUTLOOK:

The North American region accounted for 34.5% market share and dominated the global single use bioprocessing market in 2021 followed by Europe. The region is expected to maintain this trend over the forecast period and stay at the topmost position during the forecast period. The growth of the market in the region can be attributed to factors such as the proliferating demand for biopharmaceuticals due to the rapidly surging geriatric population, the growing R&D activities in the biopharmaceutical industry, the increasing number of large-scale biopharmaceutical manufacturing facilities, the rising awareness about the importance & benefits of single-use bioprocessing technologies and the spurring government investments in the development of drugs, vaccines and diagnostic tests for the treatment of COVID-19 in the region. Also, the presence of a robust commercial base for biopharmaceutical manufacturing and the growing inclination of companies towards disposable manufacturing systems are expected to further contribute towards the growth of the market during the forecast period. The U.S. is the major contributor to the growth of the market in the region.

The Asia Pacific region is projected to attain the highest growth rate in the global single use bioprocessing market during the forecast period of 2022-2030. The growth of the market in the region can be attributed to the expanding biopharmaceutical manufacturing industries in the major economies of the region, the increasing number of new product launches and the surging government support coupled with growing private investments in the region. Also, the rapidly growing old-age population, the burgeoning trend of outsourcing to the developing Asian nations and the high presence of skilled workforce are expected to significantly contribute towards the growth of the single use bioprocessing market in the region during the forecast period. India, China and Japan are the major contributors to the growth of this market in the region.

KEY COMPANIES IN SINGLE USE BIPOROCESSING MARKET:

·         G&G Technologies

·         Solida Biotech GmbH

·         Satake Chemical Equipment Mfg. Ltd.

·         Stobbe Pharma GmbH

·         General Electric Company

·         Corning

·         Entegris

·         Avantor

·         CESCO Bioengineering Co. Ltd.

·         Cellexus

·         PBS Biotech Inc.

·         Distek Inc.

·         ABEC Inc.

·         Sartorius Stedim Biotech S.A.

·         Thermo Fisher Scientific Inc.

·         Danaher Corporation

·         Merck KGaA

·         Getinge AB

·         Eppendorf AG

·         Able Corporation & Biott Corporation

·         Other Players